Prof. Fernanda Tovar-Moll, MD, PhD

Unidade de Conectividade Cerebral

Instituto D'Or de Pesquisa e Ensino e Universidade

Federal do Rio de Janeiro

Fig.1 DTI deterministic tractography shows anomalous interhemispheric connections via posterior (PC) and anterior (AC) commissures in CD. (A and B) DTI-tractography on T1 sagittal/parasagittal plane (Left), and on coronal or sagittal color-coded FA maps (Right), showing the interhemispheric midbrain bundle (A) and the interhemispheric ventral forebrain bundle (B) in yellow.
Fig. 2 rs-fMRI shows functional connectivity between the left and right parietal cortex in CD. DMN rs-fMRI statistical maps in CD (A) and control (B) groups. (C) Surface view of bilateral parietal DMN ROIs obtained from pooled data from both groups. (D–F) Views of the same DMN ROIs, overlapped with BA39 [outlined in yellow; based on Brodmann template, MRIcron V.6 (http://www.cabiatl.com/mricro/mricro/lesion.html#brod)]. Colors in A and B are arbitrary. Red and blue in C–F denote left and right hemisphe
Fig. 3 DTI and HARDI probabilistic tractography reveal anomalous interhemispheric connections via posterior and anterior commissures. (A–D) DTI analysis. Aberrant midbrain (A and B) and ventral forebrain (C) bundles reconstructed from CD individuals, crossing through the posterior (PC) and the anterior (AC) commissures. Seed ROIs positioned at the posterior parietal cortex as defined by rs-fMRI. (D) Control individual with similarly defined ROIs, showing the expected structural interhemispheric connect

Fig.1

DTI deterministic tractography shows anomalous interhemispheric connections via posterior (PC) and anterior (AC) commissures in CD. (A and B) DTI-tractography on T1 sagittal/parasagittal plane (Left), and on coronal or sagittal color-coded FA maps (Right), showing the interhemispheric midbrain bundle (A) and the interhemispheric ventral forebrain bundle (B) in yellow.

Fig. 2

rs-fMRI shows functional connectivity between the left and right parietal cortex in CD. DMN rs-fMRI statistical maps in CD (A) and control (B) groups. (C) Surface view of bilateral parietal DMN ROIs obtained from pooled data from both groups. (D–F) Views of the same DMN ROIs, overlapped with BA39 [outlined in yellow; based on Brodmann template, MRIcron V.6 (http://www.cabiatl.com/mricro/mricro/lesion.html#brod)]. Colors in A and B are arbitrary. Red and blue in C–F denote left and right hemisphe

Fig. 3

DTI and HARDI probabilistic tractography reveal anomalous interhemispheric connections via posterior and anterior commissures. (A–D) DTI analysis. Aberrant midbrain (A and B) and ventral forebrain (C) bundles reconstructed from CD individuals, crossing through the posterior (PC) and the anterior (AC) commissures. Seed ROIs positioned at the posterior parietal cortex as defined by rs-fMRI. (D) Control individual with similarly defined ROIs, showing the expected structural interhemispheric connect

Nova conexão entre os dois lados do cérebro

O estudo Structural and functional brain rewiring clarifies preserved inter-hemisphere transfer in humans born without the corpus callosum foi recentemente publicado no periódico científico internacional PNAS (Proceedings of the National Academy of Sciences). Utilizando técnicas de Ressonância Magnética, o estudo detectou a presença de rotas cerebrais (feixes) anômalas em indivíduos que não possuem o corpo caloso, uma estrutura responsável pela comunicação entre os hemisférios direito e esquerdo do cérebro.

Confira as matérias nos links abaixo:

Live Science: People Missing Brain Wiring Form Unique Neural Connections (inglês)

New Scientist: Separated at birth, but split brains build new bridges (inglês)

Science Daily: Alternative pathways let right and left communicate in early split brains (inglês)

Medical Xpress: Alternative pathways let right and left communicate in early split brains (inglês)

Science Codex: Alternative pathways let right and left communicate in early split brains (inglês)

Ciência Hoje: Novas conexões cerebrais (port.)

Estadão: Brasileiros descobrem novas estruturas no cérebro (port.)

FAPESP: Novas rotas cerebrais (port.)